Frontline Plus for Dogs

Frontline Plus for Small Dogs upto 22lbs (Orange)

Pack Size
3 Doses
6 Doses
12 Doses

Frontline Plus for Medium dogs 22 to 44lbs (Blue)

Pack Size
3 Doses
6 Doses
12 Doses

Frontline Plus for Large Dogs 44 to 88lbs (Purple)

Pack Size
3 Doses
6 Doses
12 Doses

Frontline Plus for Extra Large Dogs above 88lbs (Red)

Pack Size
3 Doses
6 Doses
12 Doses

Frontline Plus Spray for Dogs/Cats

Pack Size
100 Ml
250 Ml

Frontline Plus Flea and Tick Treatment for Dogs

Frontline Plus for dogs is a fast-acting and long-lasting solution that kills external parasites. Treating fleas and ticks, this topical solution also protects dogs against flea and tick borne diseases. Moreover, this spot-on treatment successfully destroys all life stages of fleas and prevents further re-infestation.


A product by Merial, Frontline Plus Flea and Tick Treatment for Dogs is a fast-acting, long-lasting and waterproof flea and tick protection proven to kill fleas, flea eggs, lice and ticks including those that may transmit Lyme Disease. It has been formulated with the combination of two active ingredients for dogs eight weeks of age and older. The combination of two active ingredients - Fipronil and (S)Methoprene, magically work to kill fleas within 12 hours and ticks within 48 hours of application. Fipronil kills adult fleas and ticks, and the other chemical (S)-methoprene breaks flea life cycle by attacking flea eggs and larvae. It is an easy to use topical application that stores in the oil glands of pet's skin and works for 30 days. This product is available in four different pack sizes for small, medium, large and extra large dogs.

Please note that as Merial is now part of Boehringer Ingelheim, the manufacturer’s name may differ on the product packs according to the stock availability.

Frontline Spray

Frontline Spray is a broad spectrum treatment for both cats and dogs that effectively treats flea and tick infestations in them. This long-lasting and effective formulation kills 100% fleas within a day's usage. It aids in controlling brown dog ticks when applied on a monthly basis and controls paralysis ticks in every 3 weeks of application. This recommended formula for dogs, puppies, kittens and cats also controls Flea Allergy Dermatitis (FAD) when applied on a monthly basis. More Info on Frontline Spray.


Fipronil; (S)Methoprene


Merial / Boehringer Ingelheim
  • Frontline Plus is an effective topical solution that treats various external parasites
  • Quick in its action, it removes fleas within 12 hours of application
  • It destroys the life cycle of flea along with killing its various stages
  • It effectively works for a month not allowing fleas and ticks to attack for re-infestation
  • It successfully fights against deer ticks, brown ticks, lone star ticks and American dog ticks
  • Frontline Plus also guards dogs against flea allergy dermatitis (FAD)
  • The waterproof property makes it efficient even when a dog goes for swimming or has a bath
  • Weigh dog before treating with a Frontline Plus.
  • Make dog stand in a comfortable position to apply the solution.
  • On the back of your pet, part the fur between the shoulder blades where the dog cannot lick.
  • Remove pipette from the pack and break the seal. Place the tip of the pipette on the located spot without touching hair.
  • Squeeze and empty the entire content at the spot.
  • Be careful not to touch the area until the application is wet.
  • For small and medium dogs, apply at single spot.
  • For large dogs, apply at 4-5 spots starting from the place between the shoulder blades and reaching the base of the tail.
  • It is suitable for nursing, breeding and pregnant dogs.
  • For old, debilitated and pets on other medications, consult a veterinarian.


Dosage as per dog size:

Color Code (pack color)


Dog Size


0.67 ml

0-22 lbs


1.34 ml

23-44 lbs


2.68 ml

45-88 lbs


4.02 ml

89-132 lbs

  • Frontline Plus is advisable for 8 weeks and older puppies and dogs.
  • Frontline Plus for dogs is strictly not recommended for felines.
  • Keep away from children and pets, and other animal feeds.
  • Store it in a cool and dry place away from direct flame and heat.
  • Consult a vet before treating aged, injured, debilitated dogs and pets that are on medication.
  • If swallowed accidently, contact poison control center or your physician immediately.
  • Avoid direct contact with eyes. If it enters, wash with running water for few minutes.
  • After treating dog, wash hands with soap and water.
FAQ On Frontline Plus for Dogs
Q. How safe is Frontline Plus for dogs?

A. Frontline Plus for Dogs is totally safe for all sizes and breeds of dogs. When applied monthly, it protects against parasitic infestation without any harm to your dog.

Q. How does FRONTLINE Plus kill fleas and ticks?

A. Frontline Plus contains two strong ingredients. Fipronil – a potent adulticide and (S)-Methoprene – an insect growth regulator. Once the treatment given, the strong ingredient - Fipronil triggers the nerve cells of fleas and ticks resulting into paralysis of these pests. Eventually, these parasites are destroyed. The ingredient (S)-Methoprene inhibits the growth of flea eggs and larvae. Thus, these are eliminated.

Frontline Plus easily spreads through oil glands in your pet’s skin. Slowly, it is distributed continuously for one month to your pet’s hair and skin through hair follicles. It continuously works against fleas and ticks.

Q. How quickly does Frontline Plus work on fleas and ticks?

A. Frontline Plus is a fast acting formula. It starts killing fleas 4 hours after application. It removes 100% fleas within 24 hours and ticks within 48 hours.

Q. How long Frontline Plus should be applied for before exposure to water?

A. Frontline Plus is water resistant. After application, keep your pet from getting wet for 48 hours. If you want to apply after bath, ensure that your pet is completely dry before application. It remains effective for 30 days, even if your pet swims or is bathed.

Q. Can I apply it more than once a month?

A. Frontline Plus is a monthly treatment. Therefore, it is not advisable to apply the spot-on within a month. You can re-apply after 30 days.

Q. Can I use Frontline Plus along with another flea and tick products?

A. Frontline Plus alone is powerful in treating fleas and ticks. It is better not to use any other topical flea and tick treatment along with Frontline Plus.

Ratings & Reviews

Based on 324 Review(s)

Average Rating


Ratings Overview










Most Recent Reviews
  • Cookie
    Best product
    Mar 28, 2017

    Happy that my pug does not have fleas now and it is safe. Will always buy this product.

    161 of 271 found this review helpful.
    Was this review helpful to you ? Yes No
  • Cookie
    Best for fleas
    Feb 14, 2017

    I used to use a different product, but after last year's flea population explosion in Arizona, I had to resort to the professional products. This works very well.

    152 of 246 found this review helpful.
    Was this review helpful to you ? Yes No
  • Cookie
    Works Great!
    Feb 03, 2017

    Works great and does not bother my allergies. I tried other drug but was allergic to one of the inactive ingredients.

    127 of 207 found this review helpful.
    Was this review helpful to you ? Yes No
  • Cookie
    Good Product!
    Jan 30, 2017

    My dog is an Australian cattle dog mixed named Roo and she's a love! What does this have to do with the review? Nothing. I just love my dog! And that's why I use Frontline Plus. Frontline keeps Roo free of ticks and fleas. It works very well. I tried another product for 6 months, but I've come back to Frontline. I won't be using anything else.

    147 of 258 found this review helpful.
    Was this review helpful to you ? Yes No
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