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Advantage Multi (Advocate) for Dogs
(199)

Starts From: $36.56

Advantage Multi (Advocate) Small Dogs 3-9 lbs (Green)

Pack Size
Qty.
Price
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3 DOSES
$36.56
$21.94
6 DOSES
$74.16
$44.50
12 DOSES
$148.42
$89.05

Advantage Multi (Advocate) Medium Dogs 9.1-20 lbs (Aqua)

Pack Size
Qty.
Price
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3 DOSES
$45.96
$27.58
6 DOSES
$91.08
$54.65
12 DOSES
$181.32
$108.79

Advantage Multi (Advocate) Large Dogs 20.1-55 lbs (Red)

Pack Size
Qty.
Price
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3 DOSES
$52.54
$31.52
6 DOSES
$104.24
$62.54
12 DOSES
$207.64
$124.58

Advantage Multi (Advocate) Extra Large Dogs 55.1-88 lbs (Blue)

Pack Size
Qty.
Price
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3 DOSES
$58.18
$34.91
6 DOSES
$112.70
$67.62
12 DOSES
$223.62
$134.17
6 Reasons to Choose Advantage Multi (Advocate) for Dogs?
  • Spot-on treatment for dogs.
  • Treats circulating heartworm microfilaria
  • Kills adult fleas and treats flea infestations
  • Treats and controls roundworms, hookworms and whipworms.
  • Treats and controls sarcoptic mange
  • Prevents heartworm disease
  • Overview
Overview

Advantage Multi (Advocate) Flea, Worm, and Heartworm Control

Advantage Multi (Advocate) for Dogs is a gentle, easy-to-use monthly spot-on treatment that delivers broad-spectrum parasite protection in one simple application. It starts killing fleas on contact (they don’t have to bite your pet) and helps prevent deadly heartworm disease. This topical solution also protects against most common intestinal worms, including roundworms, hookworms, and whipworms, while aiding in the prevention of flea tapeworm. Suitable for dogs and puppies 7 weeks of age and older, one application provides a full month of reliable coverage.

How it helps

Advantage Multi (imidacloprid + moxidectin) starts working fast, stopping reinfesting fleas from biting within 3–5 minutes. It treats and prevents flea infestations (Ctenocephalides spp.) and reduces the risk of Flea Allergy Dermatitis (FAD). By killing flea larvae in the dog’s surroundings, it helps break the flea life cycle. The formula prevents heartworm disease caused by Dirofilaria immitis and provides comprehensive protection against larval, immature, and adult stages of roundworms and hookworms, as well as whipworms. It also treats and controls generalized demodicosis, sarcoptic mange, ear mites, and lice. With regular monthly use, moxidectin maintains steady protection between doses.

Who it’s for

  • Dogs and puppies 7 weeks of age and older
  • Dogs needing flea and heartworm prevention
  • Dogs at risk of intestinal worms
  • Dogs requiring treatment for mites or lice
  • Available for dogs and puppies in the following weight ranges:
    • 3.0-9.0 lbs
    • 9.1–20 lbs
    • 20.1–55 lbs
    • 55.1-88.0 lbs

Your veterinarian can help determine the correct strength based on your dog’s current weight.

Why Pet Parents Choose It

  • Broad-spectrum protection in one monthly dose
  • Stops reinfesting fleas biting within 3-5 minutes
  • Kills fleas on contact—no biting required
  • Helps manage Flea Allergy Dermatitis
  • Prevents heartworm disease
  • Controls intestinal worms and external parasites
  • Easy-to-apply topical formula
  • Continuous protection between monthly doses
  • Available in different weight-specific packs for dogs of different sizes

How to Use

  • Weigh your dog to ensure you select the correct dosage.
  • Remove the required tube(s) from the package. Hold the tube upright and pull off the cap.
  • Reverse the cap, place it back on the tube, and twist to break the seal. Remove the cap once opened.
  • If your dog is wearing a Seresto collar, it does not need to be removed. Remove any other collar and replace it once the application site is dry.
  • Ensure your dog is standing for easy application.
  • Part the hair until the skin is clearly visible.
  • For dogs under 55 lbs., apply the full dose between the shoulder blades.
  • For dogs over 55 lbs., divide the dose between the shoulder blades, along the midline of the back between the hips, and at one point in between.
  • Place the tip of the tube directly on the skin and squeeze firmly twice to apply.
  • Avoid contact with your dog’s eyes or mouth.
  • Record the treatment date and repeat once every month.

Dosage:

Dog Size Dog Weight (lbs) Pack Color Tube Volume (ml) Active Ingredients (g/L) Doses Administered (Monthly)
Small Dogs 3.0 – 9.0 Green 0.4 100 g/L Imidacloprid
25 g/L Moxidectin
One
Medium Dogs 9.1 – 20.0 Aqua 1.0 100 g/L Imidacloprid
25 g/L Moxidectin
One
Large Dogs 20.1 – 55.0 Red 2.5 100 g/L Imidacloprid
25 g/L Moxidectin
One
Extra Large Dogs 55.1 – 88.0 Blue 4.0 100 g/L Imidacloprid
25 g/L Moxidectin
One
For dogs over 88.0 lbs, administer an appropriate combination of Advantage Multi (Advocate) tubes.

Safety & Care Tips

  • For external use on dogs and puppies 7 weeks of age and older only.
  • Read the label carefully before use and follow all directions.
  • Use only the correct weight-specific pack for your dog.
  • Safety has not been established for pregnant or lactating dogs.
  • Use with caution in sick, debilitated, or underweight dogs.
  • Although it may be applied to heartworm-infected dogs, a heartworm test is recommended before starting prevention. Consult your veterinarian for guidance.
  • Avoid contact with your dog’s eyes or mouth during application.
  • Do not allow children or others to touch the application site until it is completely dry.
  • Monitor your dog after application and seek veterinary advice if unusual signs occur.
  • Avoid bathing immediately after application. If washing is necessary, use a soap-free shampoo.
  • Shampooing 90 minutes after treatment does not affect heartworm prevention.
  • Water immersion or shampooing 4 days after treatment does not reduce flea treatment effectiveness; however, weekly shampooing or frequent swimming may reduce flea control duration.
  • For ongoing flea prevention, treat all dogs in the same household monthly.
  • Temporary hair loss at the application site may occur; hair typically regrows without issue.
  • Dispose of used pipettes and foil blisters by wrapping them in paper before placing in household garbage.
  • Store below 25°C (Air conditioning).
Active ingredients:
  • Imidacloprid
  • Moxidectin

Available Pack Sizes

  • 3-dose pack
  • 6-dose pack
  • 12-dose pack

Choose the appropriate pack size to ensure uninterrupted monthly protection for your dog.

Product Name Pet Size Pet Weight Color Code
Advantage Multi (Advocate) for Dogs Small 3.0 – 9.0 lbs Green
Advantage Multi (Advocate) for Dogs Medium 9.1 – 20.0 lbs Aqua
Advantage Multi (Advocate) for Dogs Large 20.1 – 55.0 lbs Red
Advantage Multi (Advocate) for Dogs Extra Large 55.1 – 88.0 lbs Blue

Frequently Asked Questions

1. What does Advantage Multi (Advocate) for Dogs protect against?

Advocate provides broad-spectrum protection against fleas, heartworm disease, roundworms, hookworms, whipworms, and also treats and controls mites and lice. It also aids in the prevention of flea tapeworm through effective flea control.

2. How often should I apply Advantage Multi (Advocate)?

Advantage Multi (Advocate) is applied once a month. Regular monthly use helps maintain continuous protection against parasites.

3. How quickly does Advantage Multi (Advocate) start working on fleas?

Advantage Multi (Advocate) kills fleas on contact, meaning they don’t need to bite your dog to be eliminated. It also helps stop reinfesting fleas from biting within minutes of contact.

4. Does my dog need a heartworm test before starting Advantage Multi (Advocate)?

While Advantage Multi (Advocate) may be used in heartworm-infected dogs, a heartworm test is generally recommended before starting any heartworm prevention program. Consult your veterinarian for advice tailored to your dog.

5. Can Advantage Multi (Advocate) help with skin issues caused by fleas?

Yes, Advantage Multi (Advocate) can be used as part of a management strategy for Flea Allergy Dermatitis (FAD) by controlling flea infestations. Consult your vet for specific treatment plan.

6. Is Advantage Multi (Advocate) safe for all dogs?

Advantage Multi (Advocate) is suitable for dogs and puppies from 7 weeks of age. However, its safety has not been established in pregnant or lactating dogs, so veterinary advice is recommended in these cases.

7. What makes Advantage Multi (Advocate) stand out from other flea and worm treatments?

Advantage Multi offers broad-spectrum protection in one monthly spot-on, covering fleas, heartworm, intestinal worms, mites, and lice, reducing the need for multiple separate treatments.

8. What should I do if my dog accidentally licks the application site?

If your dog licks the treated area, mild and temporary signs like drooling may occur due to the taste. Monitor your dog, and contact your veterinarian if you notice anything unusual or concerning.

9. Does Advantage Multi (Advocate) treat tapeworms?

It aids in the prevention of flea tapeworm by effectively controlling fleas, but it does not directly treat existing tapeworm infections.

10. Can I use Advantage Multi (Advocate) for Dogs on my cat?

No. This product is specifically formulated for dogs and should never be used on cats. Always use a product that is clearly labeled for your pet’s species.

Customer Reviews

Reviews
Rating Summary
199 Review(s)
5 star
70.85%
4 star
19.1%
3 star
10.05%
2 star
0%
1 star
0%
Overall Rating

4.6 Star

Average Customer Ratings
Quality of Product
3.6
Value of Product
3.7
Pet Satisfaction
3.7
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Convenient Product
submitted by Noemi on Jun 14, 2026

Easy way to cover multiple parasites.

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Quality of Product
2.0
Value of Product
2.0
Pet Satisfaction
2.0
Convenient Coverage
submitted by Novah on Jun 01, 2026

Combines several benefits in one dose.

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Quality of Product
2.0
Value of Product
2.0
Pet Satisfaction
2.0
Convenient Care
submitted by Mason on May 24, 2026

Covers multiple concerns in one dose.

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Quality of Product
2.0
Value of Product
2.0
Pet Satisfaction
2.0
Monthly Care
submitted by Oliver on May 21, 2026

Easy and effective.

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Quality of Product
2.0
Value of Product
2.0
Pet Satisfaction
2.0
Convenient Care
submitted by Julian on May 12, 2026

One product for multiple parasites.

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Quality of Product
2.0
Value of Product
2.0
Pet Satisfaction
2.0