Frontline Plus for Dogs provides fast-acting, reliable flea and tick protection to help keep your dog comfortable and protected month after month. Trusted by pet parents for over 20 years, this waterproof topical treatment delivers full 30-day coverage, even after exposure to water when used as directed. It kills fleas, flea eggs, flea larvae, ticks, and chewing lice through contact, so parasites do not need to bite to be eliminated. It also helps control sarcoptic mange and stops existing flea infestations while preventing new ones from developing.
Suitable for puppies 8 weeks of age and older weighing at least 5 lbs, Frontline Plus is approved for use on breeding, pregnant, and lactating dogs, offering dependable protection for dogs at every life stage.
Frontline Plus for Dogs spreads from a single point of application across your dog’s skin and coat, settling into the sebaceous glands, which act as a reservoir for continuous 30-day protection. It kills all life stages of fleas (eggs, larvae, and adults) and ticks (larvae, nymphs, and adults), including brown dog ticks, American dog ticks, lone star ticks, and deer ticks. By eliminating parasites, it also helps reduce the risk of flea allergy dermatitis and exposure to ticks that may carry diseases.
Fleas, ticks, and chewing lice are killed quickly after coming into contact with a treated dog, meaning they do not need to bite to be affected. The waterproof formula continues protecting even if your dog gets wet. Ensure your dog is completely dry at the time of application and remains dry for 24 hours afterward.
Your veterinarian can help determine the correct strength based on your dog’s current weight.
Dosage:
| Dog Weight | Dog Size | Each Pipette Contains | Dose |
| 0 to 22 lbs | Small | 0.67 ml | Once per month |
| 23 to 44 lbs | Medium | 1.34 ml | Once per month |
| 45 to 88 lbs | Large | 2.68 ml | Once per month |
| Over 89 lbs | Extra Large | 4.02 ml | Once per month |
Available in multiple pack sizes and weight ranges to suit small, medium, large, and extra-large dogs.
| Product Name | Pet Size | Pet Weight | Color Code |
| Frontline Plus for Dogs | Small Dogs | Up to 22 lbs | Orange |
| Frontline Plus for Dogs | Medium Dogs | 23 – 44 lbs | Blue |
| Frontline Plus for Dogs | Large Dogs | 45 – 88 lbs | Purple |
| Frontline Plus for Dogs | Extra Large Dogs | Over 89 lbs | Red |
Flea development varies with temperature and humidity and can take anywhere from 2 weeks to over 6 months. Existing pupae in cocoons are protected and must fully develop before emerging as adult fleas, which is why new fleas may appear for some time even after treatment.
Frontline Plus for Dogs spreads from a single point of application across your dog’s skin and coat, settling in the sebaceous glands for continuous 30-day protection. It keeps working even if your dog gets wet (apply to a dry coat and keep dry for 24 hours after application).
No. This formula is specifically designed for dogs and should not be used on cats or other animals, as formulations differ by species.
It is generally considered acceptable for use in breeding, pregnant, and lactating dogs when used as directed. Consult your veterinarian for guidance based on your dog’s individual needs.
Consult your veterinarian before combining with antibiotics, steroids, NSAIDs, antihistamines, anesthetics, oral medications, or other topical treatments.
Your dog must be dry at application and remain dry for 24 hours afterward. After that, the waterproof formula continues to protect even if your dog gets wet.
Suitable for dogs 8 weeks of age and older weighing at least 5 lbs. Always follow label directions.
Apply one dose (pipette) once every 30 days for continuous protection. Year-round use is recommended.
It is generally suitable for most breeds. If your dog has known sensitivities or medical conditions, consult your veterinarian before use.
Flea eggs can hide in carpets, bedding, and cracks. If left untreated, they hatch and restart the infestation cycle. Targeting all life stages helps break the cycle and prevent reinfestation.
Excessive scratching, biting, chewing, flea dirt (tiny dark specks), red or irritated skin, and hair loss may indicate fleas.
Untreated infestations can lead to skin irritation, allergic reactions, anemia, and increased risk of disease transmission.
Yes. Fleas can enter homes on clothing, other pets, or wildlife and infest indoor environments.
Yes. Fleas can survive indoors during winter, and ticks may remain active in cooler weather. Year-round protection is recommended.
Ticks can continue feeding and increase the risk of disease transmission. Prompt removal is important to reduce health risks.
You may be seeing new fleas emerging from the environment. In heavy infestations, new fleas may appear for several weeks while the life cycle is being broken.
It kills fleas and ticks after contact and disrupts their life cycle, but it may not prevent fleas from initially jumping onto your dog.
You can shop for Frontline Plus at competitive prices with us at PetCareSupplies. We regularly offer special deals, value packs, and seasonal savings to help make monthly flea and tick protection more affordable for pet parents. We provide genuine products along with reliable customer support for a smooth and convenient shopping experience.
4.3 
Works well and easy to apply.