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Frontline Plus for Extra Large Dogs above 88lbs (Red)
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Frontline Plus for Extra Large Dogs above 88lbs (Red)

$40.32
(580)
(580)
Select Pet's Weight:
  • Upto 22lbs
  • 23 to 44lbs
  • 45 to 88lbs
  • Over 89lbs
Select Pack:
  • 3 Doses
  • 6 Doses
$40.32
$38.30
Frontline Plus for Extra Large Dogs above 88lbs (Red)
$40.32
6 Reasons to Choose Frontline Plus?
  • Easy-to-use topical solution.
  • Treats various external parasites.
  • Eliminates fleas within 12 hours of application.
  • Remains effective for a month.
  • Treats deer ticks, brown dog ticks, lone star ticks and American dog ticks.
  • Waterproof treatment.
  • Overview
Overview

Frontline Plus for Extra Large Dogs and Puppies Over 89 lbs (Red)

Frontline Plus for Extra Large Dogs is specially formulated for extra large-sized dogs and puppies 8 weeks of age and older, weighing more than 89 lbs. Presented in the red pack, this monthly topical treatment delivers fast-acting flea and tick protection that lasts for the entire 30 days. It kills adult fleas, flea eggs, and flea larvae to help break the flea life cycle and prevent reinfestation. It also eliminates ticks and chewing lice through contact, meaning parasites do not need to bite to be affected. In addition, it aids in the control of sarcoptic mange infestations. The waterproof formula keeps working even after exposure to water when used as directed.

How it helps

Frontline Plus for Dogs spreads from a single point of application across your dog’s skin and coat, settling into the sebaceous glands, which act as a reservoir for continuous 30-day protection. It kills all life stages of fleas (eggs, larvae, and adults) and ticks (larvae, nymphs, and adults), including brown dog ticks, American dog ticks, lone star ticks, and deer ticks. By eliminating parasites, it also helps control sarcoptic mange infestations and reduces the risk of flea allergy dermatitis and exposure to ticks that may carry diseases.

Who it’s for

  • Extra large dogs and puppies 8 weeks of age and older, weighing over 89 lbs

Your veterinarian can help determine the correct strength based on your dog’s current weight.

Why Pet Parents Choose It

  • Fast-acting flea and tick protection
  • Provides continuous protection for 30 days
  • Waterproof formula
  • Kills fleas, flea eggs, and flea larvae
  • Prevents all flea life stages from developing
  • Stops existing infestations and helps prevent new ones
  • Kills ticks at larval, nymph, and adult stages
  • Rapidly eliminates chewing lice
  • Aids in the control of sarcoptic mange
  • Trusted by pet owners for over 20 years

How to Use

  • Ensure your dog is completely dry before application.
  • Separate one blister using scissors.
  • Cut along the dotted line and peel back the foil to remove the applicator.
  • Hold the applicator upright (foil side facing you) and snap off the tip.
  • Part your dog’s hair between the shoulder blades.
  • Place the tip directly on the skin and squeeze to apply the entire contents in one spot.
  • Do not apply on top of the hair coat.
  • Keep your dog dry for 24 hours after application.
  • Avoid contact with the treated area until completely dry.
  • Reapply every 30 days for continuous protection.

Dosage:

Dog Weight Dog Size Each Pipette Contains Dose
0 to 22 lbs Small 0.67 ml Once per month
23 to 44 lbs Medium 1.34 ml Once per month
45 to 88 lbs Large 2.68 ml Once per month
Over 89 lbs Extra Large 4.02 ml Once per month

Safety & Care Tips

  • Read the entire label and directions before use.
  • For external use on dogs only.
  • Do not use on puppies under 8 weeks of age or weighing under 5 lbs.
  • Do not use more than one applicator per dog per month.
  • Avoid contact with your dog’s eyes or mouth.
  • Wash hands after application.
  • Consult your veterinarian before use on medicated, debilitated, aged, pregnant, or nursing dogs.
  • Pets may experience some temporary irritation at the site of application. Consult your veterinarian if signs persist or worsen within a few days.
  • Keep out of reach of children.
  • Store in a cool, dry place out of reach of children.
Active Ingredient :
  • Fipronil
  • (S)-Methoprene

Available Pack Sizes

  • 3-dose pack
  • 6-dose pack

Available in multiple pack sizes and weight ranges to suit small, medium, large, and extra-large dogs.

Product Name Pet Size Pet Weight Color Code
Frontline Plus for Dogs Small Dogs Up to 22 lbs Orange
Frontline Plus for Dogs Medium Dogs 23 – 44 lbs Blue
Frontline Plus for Dogs Large Dogs 45 – 88 lbs Purple
Frontline Plus for Dogs Extra Large Dogs Over 89 lbs Red

Customer Reviews

Reviews
Rating Summary
580 Review(s)
5 star
53.1%
4 star
25.69%
3 star
20.69%
2 star
0.17%
1 star
0.34%
Overall Rating

4.3 Star

Average Customer Ratings
Quality of Product
3.5
Value of Product
3.6
Pet Satisfaction
3.7
Sort By:
Trusted Companion
submitted by Callum on Jun 06, 2026

Has remained dependable over the years.

Was this review helpful?
Quality of Product
2.0
Value of Product
2.0
Pet Satisfaction
2.0
Consistent Support
submitted by Linora on Jun 05, 2026

Continues to work well for us.

Was this review helpful?
Quality of Product
2.0
Value of Product
2.0
Pet Satisfaction
2.0
Trusted Standby
submitted by Henry on May 26, 2026

Been using it with consistent results.

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Quality of Product
2.0
Value of Product
2.0
Pet Satisfaction
2.0
Classic Choice
submitted by Kevin on May 17, 2026

Works well and easy to apply.

Was this review helpful?
Quality of Product
2.0
Value of Product
2.0
Pet Satisfaction
2.0
Trusted Treatment
submitted by Chloe on May 14, 2026

Works well for monthly flea control.

Was this review helpful?
Quality of Product
2.0
Value of Product
2.0
Pet Satisfaction
2.0