Comfortis Plus (Trifexis)

Comfortis Plus (Trifexis) For Large Dogs 18.1-27 Kg (40.1 - 60 lbs) Blue

Reviews: 15
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Comfortis Plus (Trifexis)

Comfortis Plus is an easy-to-dose meat-flavored monthly treatment for dogs. It protects your dogs against fleas, heartworms, and intestinal worms like hookworms, roundworms, whipworms. It starts killing fleas in just 30 minutes of administration, controls flea infestation for a month and also aids in the treatment of flea allergy dermatitis. Comfortis Plus is suitable for use for puppies over 8 weeks of age.

How Comfortis Plus for Dogs Works?

Comfortis Plus contains two key ingredients: spinosad and milbemycin oxime. The active ingredient, spinosad, is an insecticide that attacks the neurons and causes paralysis of the parasite. The second main ingredient, milbemycin oxime, treats other intestinal worms and immature forms of heartworms.


  • Easy oral administration
  • Monthly treatment
  • 3-in1 parasite protection
  • Effectively kills and eliminates fleas
  • Begins to kill fleas in just 30 minutes
  • Provides relief from the symptoms of Flea Allergy Dermatitis as a direct result of eliminating fleas
  • Treats intestinal worms like hookworms, roundworms, whipworms
  • Treats immature forms of heartworms
  • Select the correct dosage as per the dog’s weight
  • Administer directly into the mouth or by mixing it with your dog’s food
  • Dogs should be tested for heartworms if they may have a pre-existing heartworm infestation
  • Strictly to be used for dogs only
  • Consult your veterinarian before starting any treatment
  • Suitable only for dogs over 8 weeks of age and weighing at least 2.3kg
  • Use with caution in breeding & lactating dogs and in dogs with pre-existing epilepsy
  • Concurrent use of Comfortis plus is not recommended with Ivermectin

Ratings & Reviews

Based on 15 Review(s)

Average Rating


Ratings Overview










Most Recent Reviews
  • Cookie
    I'm a beleiver
    Oct 28, 2022

    Nothing ever worked for my boy but comfortis plus changed my perception towards preventives!

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  • Cookie
    Comfortis Plus
    Oct 06, 2022

    Great product started working within an hour so happy with the results. Company is very easy to deal with and ships on time very pleased. Will recommend to others and use you again.

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  • Cookie
    Pet medicine
    Sep 17, 2022

    Son was pleased to pay a good price for quality product.

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  • Cookie
    It works!
    Aug 27, 2022

    These tablets are amazing. I'd recommend.

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  • Cookie
    Comfortis Plus for large dogs
    Aug 14, 2022

    We have used comfortis for the last ten years for our boxer. No fleas or ticks ever. Our vet said they couldn't get it any more. After checking on the internet found out it is no longer being made. We then found Comfortus Plus. Since we were already using heartguard this will take take the place of it. the one pill takes care of it all.

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